Depression is a major medical condition and severe refractory depression is a difficult condition to treat. Electroconvulsive therapy may treat refractory depression but has limitations in access and cost. Join host, Geoff Wall, as he evaluates ketamine as a treatment option for severe depression.
Ketamine has been shown to treat depression and was recently compared to ECT in a non-inferiority trial. Relapse rates and adverse drug reaction rates between treatments were similar.
Geoff Wall, PharmD, BCPS, FCCP, BCGP
Professor of Pharmacy Practice, Drake University
Internal Medicine/Critical Care, UnityPoint Health
Anand A, Mathew SJ, Sanacora G, et al. Ketamine versus ECT for Nonpsychotic Treatment-Resistant Major Depression. N Engl J Med. 2023 Jun 22;388(25):2315-2325. doi: 10.1056/NEJMoa2302399. Epub 2023 May 24. PMID: 37224232.
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Upon successful completion of this knowledge-based activity, participants should be able to:
1. Discuss the history and barriers of ECT for severe depression
2. Describe the results of ketamine vs ECT in depression
0.05 CEU/0.5 Hr
Initial release date: 7/24/2023
Expiration date: 7/24/2024
Additional CPE details can be found here.