CEimpact Podcast
The CEimpact Podcast features two shows - GameChangers and Precept2Practice!
The GameChangers Clinical Conversations podcast, hosted by Josh Kinsey, features the latest game-changing pharmacotherapy advances impacting patient care. New episodes arrive every Monday. Pharmacist By Design™ subscribers can earn CE credit for each episode.
The Precept2Practice podcast, hosted by Kathy Scott, features information and resources for preceptors of students and residents. New episodes arrive on the third Wednesday of every month. Preceptor By Design™ subscribers can earn CE credit for each episode.
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CEimpact Podcast
Thrombolytic Use in Persons with Stroke and Direct Oral Anticoagulants
Patient use of any anticoagulation during an acute stroke is a contraindication for the use of thrombolytics or clot busters. Recent meta-analyses and animal studies raise the question of this contraindication. Join guest, Geoff Wall, as he examines the data on Direct Oral Anticoagulants (DOACs) and thrombolytics.
The GameChanger
DOACs have a significantly smaller intracranial hemorrhage (ICH) risk compared to warfarin and this benefit may translate to risk of bleed with thrombolytics. A new study found a numerically decreased risk of ICH in patients with DOACs compared to controls.
Show Segments
00:00 - Introductions
01:07 - Current Practices with Thrombolytics
05:05 - Looking at the Study
19:45 - The GameChanger: Decreased ICH Risk?
23:30 - Study Limitations
26:11 - Connecting to Practice
27:01 - Closing Remarks
Host
Geoff Wall, PharmD, BCPS, FCCP, CGP
Professor of Pharmacy Practice, Drake University
Internal Medicine/Critical Care, UnityPoint Health
References and Resources
Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants
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CPE (Pharmacist)
Get a membership & earn CE for GameChangers Podcast episodes (30 mins/episode)
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CE Information
Learning Objectives
Upon successful completion of this knowledge-based activity, participants should be able to:
1. Discuss the theory about why DOACs may not increase risk of intracranial bleed in stroke patients receiving thrombolytics
2. Describe the limitations of the Meinel et al study
0.05 CEU/0.5 Hr
UAN: 0107-0000-23-064-H01-P
Initial release date: 02/13/2023
Expiration date: 02/13/2024
Additional CPE and CME details can be found here.