Hydrochlorothiazide is the go-to thiazide for hypertension control despite better data for chlorthalidone. Join host Geoff Wall as he evaluates the new randomized controlled study to determine what is the best thiazide.
Several pharmacologic differences exist between hydrochlorothiazide and chlorthalidone. The new DCP Study did not find any differences in cardiovascular outcomes.
00:00 - Introductions
02:20 - History of HCTZ vs Chlorthalidone
05:26 - The Diuretic Comparison Project: HCTZ vs Chlorthalidone
12:27 - The GameChanger: DCP Results
19:48 - Connecting to Practice: Choosing Between the Two
21:47 - Closing Remarks
Geoff Wall, PharmD, BCPS, FCCP, CGP
Professor of Pharmacy Practice, Drake University
Internal Medicine/Critical Care, UnityPoint Health
References and Resources
Chlorthalidone vs. Hydrochlorothiazide for Hypertension-Cardiovascular Events.
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Upon successful completion of this knowledge-based activity, participants should be able to:
1. Discuss the pharmacologic differences of hydrochlorothiazide and chlorthalidone
2. Apply the results of the DCP Study to clinical practice
0.05 CEU/0.5 Hr
Initial release date: 01/30/2023
Expiration date: 01/30/2024
Additional CPE and CME details can be found here.
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